Peer-reviewed veterinary case report
Contrast ultrasound to check gut blood flow in dogs with inflammatory
By Linta, Nikolina et al.·Published in Journal of veterinary internal medicine·2021·Department of Veterinary Medical Science, Italy·View original on PubMed →
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Original publication title: Contrast-enhanced ultrasonography in dogs with inflammatory bowel disease.
- Species:
- dog
Plain-English summary
A group of dogs with inflammatory bowel disease (IBD) underwent a special ultrasound test called contrast-enhanced ultrasonography (CEUS) to check how well blood was flowing in their intestines. The results showed that while the test could tell the difference between healthy dogs and those with IBD, it didn't help track how well the dogs were responding to treatment over time. After two months of standardized treatment, the blood flow patterns in the intestines of the IBD dogs remained similar to their initial readings. This means that while CEUS can help diagnose IBD, it may not be useful for monitoring treatment progress.
People also search for: dog inflammatory bowel disease treatment · how to manage IBD in dogs · ultrasound for dog gut health
Abstract
BACKGROUND: Contrast-enhanced ultrasonography (CEUS) is used to evaluate vascularity of the gastrointestinal wall in neoplastic and inflammatory diseases. OBJECTIVE: To assess the feasibility of CEUS for the evaluation of duodenal perfusion in dogs with inflammatory bowel disease (IBD). ANIMALS: Forty-two dogs with IBD and 20 clinically healthy dogs. METHODS: All CEUS studies of the duodenum were analyzed to obtain time-intensity curves and perfusion parameters. The procedure was repeated in 12 IBD dogs 2 months after a standardized treatment. RESULTS: On CEUS, the duodenal wall showed a typical perfusion pattern characterized by a radial and simultaneous enhancement of the wall in all dogs. On qualitative assessment, no differences were observed in contrast medium distribution between healthy and affected dogs, or between dogs with IBD before and after treatment. Peak intensity (PI) and area under the curve (AUC) significantly differed between healthy (PI = 3.58 arbitrary units [au; 1.86-4.93 au] and AUC = 47.63 au seconds [aus, 22.68-62.15]) and affected dogs (PI = 5.10 au [0.63-15.16 au] and AUC = 63.62 aus [5.31-212.20 aus]; P = .03 and .03, respectively). No significant differences were found for the perfusion parameters before and after treatment. CONCLUSIONS AND CLINICAL IMPORTANCE: We showed that CEUS allows discrimination between IBD affected dogs and healthy dogs by evaluation of time-intensity curves, but did not provide useful information for monitoring therapeutic response. The qualitative assessment identified no significant differences between healthy and affected dogs, or between dogs before and after treatment.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34432324/