Peer-reviewed veterinary case report
Contrasting roles of IFN-gamma in murine models of autoimmune thyroid diseases.
- Journal:
- Thyroid : official journal of the American Thyroid Association
- Year:
- 2007
- Authors:
- Fang, Yujiang et al.
- Affiliation:
- Department of Internal Medicine · United States
- Species:
- rodent
Abstract
Interferon-gamma (IFN-gamma), a prototypic proinflammatory cytokine produced by several different cell types, including the Th1 subset of CD4(+) T cells, plays an important role in inflammation and autoimmune diseases. This review focuses on the varied and often contrasting roles of IFN-gamma in three murine models of autoimmune thyroid disease, experimentally induced autoimmune thyroiditis, the model of iodine-induced spontaneous autoimmune thyroiditis in NOD.H-2h4 mice and several different murine models of Graves' disease.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17910526/