Peer-reviewed veterinary case report
Factors linked to infection after dog knee surgery (TPLO)
By Hagen, Chris R M et al.·Published in Veterinary surgery : VS·2020·Department of Clinical Studies, Canada·View original on PubMed →
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Original publication title: Contributing factors to surgical site infection after tibial plateau leveling osteotomy: A follow-up retrospective study.
- Species:
- dog
Plain-English summary
A group of dogs that had surgery to fix knee problems (tibial plateau leveling osteotomy or TPLO) were studied to see how often they developed infections at the surgery site. Out of 659 surgeries, 71 dogs (about 11%) got infections, with some caused by a resistant bacteria. The study found that giving antibiotics before and after surgery helped reduce the chance of infection, especially when the antibiotics were given more than an hour before the surgery started. This means that proper timing of antibiotic treatment is important for keeping dogs safe from infections after this type of surgery.
People also search for: dog knee surgery infection · TPLO surgery antibiotics · dog surgical site infection prevention
Abstract
OBJECTIVE: To identify factors associated with surgical site infection (SSI) after tibial plateau leveling osteotomy (TPLO). STUDY DESIGN: Retrospective case series. ANIMALS: Dogs (n = 541) that underwent TPLO (n = 659). METHODS: Medical records of dogs that underwent TPLO from 2011-2018 were reviewed. Data collected included perioperative and postoperative antimicrobial administration, stifle inspection, duration of surgery and anesthesia, comorbidities, and development of SSI including timing, microbiological investigation, and implant removal. Referring veterinarians were contacted for all dogs without a recorded return visit. Risk factors for SSI were assessed by using a multivariable logistic regression model built by using a stepwise approach. RESULTS: Surgical site infection was documented in 71 of 659 (11%) TPLO, with methicillin-resistant Staphylococcus pseudintermedius accounting for 20 of 71 (28%) infections. Protective factors against SSI included administration of postoperative antimicrobials (odds ratio [OR] 0.263; 95% CI = 0.157, 0.442) and timing of preoperative antimicrobial administration. Preoperative antimicrobial timing was protective against SSI when it was administered more than 60 minutes before the first incision compared with administration within 30 minutes (OR 0.275; 95% CI = 0.112, 0.676) or within 60 minutes (OR 0.419; 95% CI = 0.189, 0.929) of the first incision. CONCLUSION: Early administration of perioperative antimicrobials and postoperative antimicrobial administration were protective against SSI after TPLO. CLINICAL SIGNIFICANCE: Antimicrobials can influence the risk of SSI after TPLO. Perioperative and postoperative antimicrobial administration timing should be considered to reduce SSI.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32359005/