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Peer-reviewed veterinary case report

How 2% lidocaine gel causes temporary cornea numbness in healthy dogs

By Robin, Marie-Claire et al.·Published in Veterinary ophthalmology·2020·Small Animal Clinic, France·View original on PubMed

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Original publication title: Corneal anesthesia associated with topical application of 2% lidocaine nonophthalmic gel to healthy canine eyes.

Species:
dog

Plain-English summary

Nineteen healthy adult Beagles had 2% lidocaine gel applied to one eye to test how well it numbed the cornea. The dogs showed complete loss of sensitivity in the treated eye just one minute after application, and this numbness lasted for about 25 minutes. Overall, the corneal sensitivity was significantly reduced for nearly an hour. Some minor, temporary eye surface issues were noted, but these were not serious and resolved quickly. This gel appears to be effective and safe for numbing the eyes in dogs without existing eye problems.

People also search for: dog eye numbing gel · Beagle eye treatment · lidocaine for dog eye procedures

Abstract

OBJECTIVE: To assess the degree and duration of corneal anesthesia induced by topical application of 2% lidocaine gel to the healthy canine eye. ANIMALS: Nineteen adult Beagles free of ocular abnormalities. PROCEDURES: Baseline corneal touch threshold (CTT) was measured bilaterally with a Cochet-Bonnet aesthesiometer. The 2% lidocaine gel (0.1 mL) was applied to one eye, randomly assigned, and the same volume of a lubricant gel was applied to the opposite eye. The CTT measurements were repeated bilaterally within 1 minute, after drug application, and every 5 minutes, until the baseline corneal sensitivity was restored. The potential for local adverse effects was evaluated. RESULTS: Complete desensitization of the cornea (CTT = 0) was achieved one minute after lidocaine gel application and was maintained during 25.3 ± 12.5 minutes. Overall, the corneal sensitivity was significantly decreased for 58.4 ± 16.6 minutes compared with baseline level. Minor and reversible punctate epithelial erosions of the cornea were observed in the two treatment groups and were attributed to the anesthetic effect and the aesthesiometry procedure. CONCLUSIONS: In the current study, the 2% lidocaine gel provided a sustained, deep and well-tolerated corneal anesthesia in ophthalmically normal dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32267080/