Peer-reviewed veterinary case report
Corneal squamous cell cancer in two dogs with eye irritation
By Takiyama, Naoaki et al.·Published in Veterinary ophthalmology·2010·Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Corneal squamous cell carcinoma in two dogs.
- Species:
- dog
Plain-English summary
Two dogs were diagnosed with corneal squamous cell carcinoma (a type of eye cancer) after showing signs of chronic eye irritation and pigmentary keratitis (a condition that causes dark spots on the cornea). The tumors were surgically removed, and to help with ongoing irritation, a special eye drop solution was used. After more than 15 months, neither dog showed any signs of cancer returning, indicating that the treatment was successful.
People also search for: dog eye cancer treatment · corneal squamous cell carcinoma in dogs · chronic eye irritation in dogs · dog keratitis symptoms
Abstract
PURPOSE: To report two cases of corneal squamous cell carcinoma (SCC) in dogs. METHODS: Corneal tumors were resected by superficial keratectomy in two cases. Immunohistochemistry of the corneal tissues was performed using anti-p53 antibody. RESULTS: The prominent features of the cases were a clinical history of pigmentary keratitis and chronic keratitis. In each case, a corneal mass was surgically removed with a superficial keratectomy and histologically diagnosed as corneal SCC. Both masses were negative for p53. To reduce chronic corneal irritation, 0.1% hyaluronate sodium ophthalmic solution was applied. After more than 15 months of postsurgical follow-up there has been no recurrence of either neoplasm. CONCLUSION AND DISCUSSION: Chronic corneal irritation was suspected as the primary etiology for the corneal SCC. Appropriate surgical removal of the mass and subsequent conservative treatment for keratitis provided effective therapy in these two cases.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20618806/