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Peer-reviewed veterinary case report

Coronoid process sclerosis predicts elbow disease risk in Labradors

By Deboutte, Birgit et al.·Published in Frontiers in veterinary science·2026·Department of Veterinary and Biosciences·View original on PubMed

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Original publication title: Coronoid process sclerosis as a reproducible and highly heritable risk predictor of medial coronoid disease in labrador retrievers.

Species:
dog
Hip dysplasiaMovement & jointsDogs

Plain-English summary

A group of Labrador Retrievers was studied to find a way to predict which puppies might develop elbow problems, specifically medial coronoid disease (MCD), which is a common issue in this breed. Researchers found that a specific change in the elbow joint called sclerosis of the coronoid process was a strong indicator of whether the puppies would be at risk for MCD. By using advanced imaging techniques like CT scans instead of regular X-rays, breeders can better select dogs for breeding to help reduce the chances of MCD in future generations. This could lead to healthier puppies and fewer elbow problems as they grow.

People also search for: Labrador elbow dysplasia symptoms · medial coronoid disease in puppies · CT scan for dog elbow problems

Abstract

INTRODUCTION: Canine elbow dysplasia (CED) is an important cause of exclusion during training for assistance dogs, making improved selection strategies essential for these programs. Although selective breeding has been applied for decades, progress in reducing CED prevalence has been limited, partly because many breeding programs rely on radiography rather than the more accurate computed tomography (CT). This study aimed to evaluate CT-based scoring of specific features in breeding dogs, as a tool to reduce the prevalence of medial coronoid disease (MCD)-the most common manifestation of CED-in their offspring. METHODS: An observational study was conducted on a group of Labrador Retrievers from two assistance dog breeding programs where CT is used routinely for screening. Six CT features were scored in parents without primary lesions, and their association with MCD occurrence in offspring was analyzed. Inter-rater agreement was assessed, and for features deemed reproducible, CT reports from a subset of offspring were rescored and narrow-sense heritability was estimated using Bayesian statistical methods. RESULTS: Sclerosis of the coronoid process (CP) was the strongest predictor of offspring MCD risk [odds ratio = 4.6, 95% CI = (1.3; 16.5)], had sufficiently high inter-rater agreement and showed high heritability. DISCUSSION: CP sclerosis proved to be a significant and reproducible phenotype with high heritability, encouraging the use of this feature in CT-based scoring protocols in breeding programs to improve selection strategies and accelerate progress in reducing MCD prevalence.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41737679/