Peer-reviewed veterinary case report
Dog with chronic bloody diarrhea diagnosed with granulomatous colitis
By C. Sims et al.·Published in Veterinary clinical pathology·2021·View original on Semantic Scholar →
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Original publication title: Correlation of cytology to histology in a case of canine granulomatous colitis in a Boxer dog.
- Species:
- dog
Plain-English summary
A 2-year-old mixed breed dog was brought in for chronic diarrhea with blood in the stool and weight loss. Tests showed signs of a condition called granulomatous colitis, which was linked to a specific type of bacteria. The dog was treated with an antibiotic called enrofloxacin, and after about six weeks, he showed nearly complete improvement in his symptoms. This case highlights how important it is to identify the right bacteria to effectively treat this uncommon intestinal issue.
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Abstract
A 2-year-old castrated male mixed breed dog presented to the North Carolina State Veterinary Teaching Hospital for chronic diarrhea with hematochezia and weight loss. Cytology performed on a rectal scraping revealed macrophages containing magenta, light pink, and variably blue granular inclusions, and phagocytosed material concerning for infectious organisms. Histopathology was consistent with granulomatous colitis and identified intra-histiocytic bacterial organisms, confirmed by fluorescent in situ hybridization (FISH)-tissue culture-confirmed Escherichia coli. Based on these findings, a diagnosis of granulomatous colitis was made. The patient was successfully treated with oral enrofloxacin, and near-complete remission of signs was achieved within 6 weeks. This report describes a case of granulomatous colitis in a mixed breed dog, and is the first published description of the cytologic features of this uncommon disease, offering a valuable cytologic-histologic correlation. In this case, the cytology was helpful in identifying features consistent with granulomatous colitis and prioritizing the differential diagnoses and diagnostic plan.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/34664295