Peer-reviewed veterinary case report
Corynebacterium pseudotuberculosis. A new cause of infectious and eosinophilic pneumonia.
- Journal:
- The American journal of medicine
- Year:
- 1979
- Authors:
- Keslin, M H et al.
Plain-English summary
A 28-year-old veterinary student became very sick with a high fever, a cough, and an increase in a type of white blood cell called eosinophils, which can indicate an allergic reaction or infection. Doctors found a bacteria called Corynebacterium pseudotuberculosis, which usually causes infections in livestock, in samples taken from the student's lungs. This bacteria has never been known to cause pneumonia in people before, as it typically leads to swollen lymph nodes instead. After starting treatment with erythromycin, the student's eosinophil levels and specific antibodies against the bacteria improved, although another type of antibody continued to rise. Overall, the treatment was effective in reducing some of the symptoms and the immune response to the bacteria.
Abstract
A 28 year old veterinary medical student experienced spiking fever, cough, peripheral blood eosinophilia and an eosinophilic pulmonary infiltrate. Corynebacterium pseudotuberculosis was isolated from a transtracheal aspirate and bronchoscopy washings. C. pseudotuberculosis, a pathogen responsible for lymphadenitis in livestock, has never been reported to cause pneumonia in man. In the four cases of C. pseudotuberculosis previously reported, lymphadenitis was the chief clinical presentation. In our patient specific antibodies against the isolated C. pseudotuberculosis developed but not against the other corynebacteria. With erythromycin therapy, the peripheral blood eosinophilia and IgE anti-C. pseudotuberculosis titer decreased whereas the IgG titer continued to increase.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/463927/