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Peer-reviewed veterinary case report

CPD article: Anaemia of renal disease: pathophysiology and treatment updates

Journal:
Companion Animal
Year:
2015
Authors:
Chalhoub, Serge & Langston, Cathy
Affiliation:
Department of Veterinary Clinical and Diagnostic Sciences, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada · Canada

Abstract

Chronic kidney disease (CKD) often leads to renal anaemia, due to gradual reduction of erythropoietin-producing renal cells. About 15–30% of geriatric cats develop CKD, with renal disease being the primary cause of death of older cats. Of those cats with CKD, up to 65% in later-stage CKD will develop renal anaemia. Recognising and treating anaemia of renal disease is an important part of CKD therapy in both dogs and cats. The use of erythropoiesis-stimulating agents (ESAs) is standard-of-care in humans and becoming more used in veterinary medicine. Darbepoetin alfa (DA) has been shown to be effective in the treatment of renal anaemia.

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Original publication: https://doi.org/10.12968/coan.2015.20.8.448