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Peer-reviewed veterinary case report

Creation of four experimental aneurysms with different hemodynamics in one dog.

Journal:
AJNR. American journal of neuroradiology
Year:
2005
Authors:
Shin, Yong Sam et al.
Affiliation:
Beth Israel Hyman-Newman Institute for Neurology and Neurosurgery · United States
Species:
dog

Abstract

We developed an experimental canine model in which four types of aneurysm--bifurcation, side-wall, small branch-artery, and arterial-stump--were surgically created in the same animal. These experimental aneurysms are exposed to simultaneous but different hemodynamic stresses correlating to human intracranial aneurysms in different locations. Because this model allowed for the creation of four aneurysms, each with different hemodynamic features, it seems to offer advantages from ones previously described. This model may foster investigation of new and current endovascular devices.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16091527/