Peer-reviewed veterinary case report
Cross-protection of a porcine circovirus types 2a/b (PCV-2a/b) andtrivalent vaccine against a dual PCV-2e andchallenge.
- Journal:
- Canadian journal of veterinary research = Revue canadienne de recherche veterinaire
- Year:
- 2023
- Authors:
- Suh, Jeongmin et al.
- Affiliation:
- Department of Veterinary Pathology · South Korea
Abstract
The purpose of this experimental study was to determine the cross-protection of a new trivalent vaccine containing porcine circovirus types 2a/b (PCV-2a/b) andPigs were vaccinated intramuscularly at 21 days of age, then challenged at 42 days of age with a dual PCV-2e andchallenge. Growth performance was significantly improved during the experimental period (21 to 63 days of age) in vaccinated-challenged pigs compared to unvaccinated-challenged pigs. Pigs that were vaccinated and challenged elicited a significant amount of PCV-2e- and-specific interferon-γ secreting cells (IFN-γ-SC) and reduced the levels of PCV-2e viremia and laryngeal shedding. The results of the present study demonstrated that a trivalent vaccine provided cross-protection against a dual PCV-2e andchallenge.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/37790269/