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Peer-reviewed veterinary case report

Cat with cryptococcosis and feline immunodeficiency virus

By Cabañes, F J et al.·Published in Mycoses·1995·Faculty of Veterinary Medicine, Spain·View original on PubMed

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Original publication title: Cryptococcosis in a cat seropositive for feline immunodeficiency virus.

Species:
cat
FIV and FeLVBreathing & coughCats

Plain-English summary

A 5-year-old female Siamese cat was brought to the vet after suffering from bronchopneumonia for 20 days without improvement from antibiotics. The cat had swollen lymph nodes and tests revealed a fungal infection caused by Cryptococcus neoformans, which is more common in cats with feline immunodeficiency virus (FIV). The vet treated her with an antifungal medication called ketoconazole for three months, and she initially seemed to recover. Unfortunately, three months later, she was found in a very serious condition, and the owners chose to euthanize her.

People also search for: cat bronchopneumonia treatment · Siamese cat swollen lymph nodes · feline immunodeficiency virus symptoms

Abstract

A 5-year-old female Siamese cat was presented to the veterinary teaching hospital with a history of bronchopneumonia for 20 days. The cat had not responded to antibacterial chemotherapy and had developed a pronounced submandibular lymphadenopathy. Characteristically encapsulated yeast cells with narrow-necked buds were clearly seen in a fine-needle aspirate of the lymph node with an India ink preparation. Cryptococcus neoformans var. neoformans was identified. Susceptibility tests on the isolated strain were performed using antifungal tablets. The strain was sensitive to amphotericin B, fluconazole, itraconazole and ketoconazole and was resistant to 5-fluorocytosine. The cat was positive for feline immunodeficiency virus. Nevertheless, the cat was treated with ketoconazole for 3 months and apparently recovered. Three months later the animal was presented in a precomatose state. The owners refused to treat the animal and the cat was destroyed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7477089/