Peer-reviewed veterinary case report
Cryptococcosis in dogs and cats - symptoms and treatment
By Faggi, E et al.·Published in Mycoses·1993·Istituto di Microbiologia dell'Università, Italy·View original on PubMed →
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Original publication title: Cryptococcosis in domestic mammals.
Plain-English summary
A 5-year-old dog with skin lesions was diagnosed with cryptococcosis, a fungal infection that can affect various parts of the body. This dog, along with two others from the same litter, had been exposed to contaminated soil, which likely contributed to their illness. The initial treatment with flucytosine worked for a while, but the dog experienced a relapse. Eventually, switching to fluconazole successfully treated the infection.
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Abstract
After a brief review of cryptococcosis in dogs and cats from the literature from 1980 to 92, three cases in dogs (two epidemiologically strictly connected) and two in cats are reported. In the three dogs and in one of the two cats lesions were seen in many sites, but only one dog and one cat had a central nervous system localization. The cutis was affected in the three dogs and in one cat; in two of the dogs it was probably the primary lesion, and in the cat it was the only lesion. An unidentified genetic defect was probably the predisposing factor in two of the dogs of the same litter, exposed to soil cryptococcal contamination (from pigeon guano); a third dog, of different breeding, was not infected. Steroid treatment was predisposing in one cat. Flucytosine treatment was initially successful in two dogs, but in both relapses were reported; in one dog fluconazole treatment was successful. The isolates, before and after treatment, demonstrated a large increase in flucytosine MIC, strictly connected with the relapse.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8264712/