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Peer-reviewed veterinary case report

Goat with swollen carpal joint diagnosed with Cryptococcus gattii

By Bosch, Sarah N et al.·Published in Veterinary clinical pathology·2025·Department of Comparative, United States·View original on PubMed

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Original publication title: Cryptococcus gattii Infection in the Carpal Joint of a Goat.

Species:
goat
Movement & joints

Plain-English summary

A 5-year-old LaMancha goat buck was brought in for worsening lameness and swelling in the left front leg over the past week. Tests showed that the swelling was caused by a fungal infection from a type of yeast called Cryptococcus gattii. Unfortunately, the goat's condition was very serious, and it was euthanized due to a poor prognosis. This case is notable as it is the first reported instance of this particular yeast infection affecting a goat's joint.

People also search for: goat lameness treatment · goat joint swelling causes · Cryptococcus gattii in goats

Abstract

A 5-year-old LaMancha goat buck presented for evaluation of a 1-week history of progressive lameness and carpal swelling in the left thoracic limb. Cytology performed on an aspirate from the left radiocarpal joint identified abundant round to oval, thickly encapsulated, extracellular yeast organisms that occasionally exhibited narrow-based budding, features compatible with Cryptococcus spp. yeast. The patient was euthanized due to poor prognosis, and a necropsy was performed. Histopathology confirmed the presence of numerous fungal yeast associated with the left radiocarpal joint. A cryptococcal serum latex agglutination test was negative. However, panfungal PCR and fungal culture identified the organisms as Cryptococcus gattii. This report describes, for the first time, a case of a C. gattii infection affecting the joint of a goat.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40999868/