Peer-reviewed veterinary case report
Dog in Oregon diagnosed with Cryptococcus gattii infection
By Byrnes, Edmond J et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2009·Department of Molecular Genetics and Microbiology, United States·View original on PubMed →
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Original publication title: Cryptococcus gattii with bimorphic colony types in a dog in western Oregon: additional evidence for expansion of the Vancouver Island outbreak.
- Species:
- dog
Plain-English summary
A 1.5-year-old dog in Oregon was diagnosed with a serious fungal infection called cryptococcosis after showing symptoms related to a mass in its head. The vet collected samples from the dog's nose and the mass, which revealed two types of the fungus, one of which was pigmented and the other unpigmented. Both types were found to be genetically identical and linked to a known outbreak from Vancouver Island. The dog received treatment for the infection, but the details of the outcome were not specified.
People also search for: dog fungal infection symptoms · cryptococcosis in dogs treatment · Oregon dog illness outbreak
Abstract
Cryptococcus gattii was isolated from a 1.5-year-old dog with systemic cryptococcosis in Oregon. The dog had no link to Vancouver Island or British Columbia, Canada. Samples from a nasal swab and from a granulomatous mass within the cranial cavity were pooled for culture. Colonies on Sabouraud dextrose agar were mucoid and exhibited bimorphic morphology, melanin-pigmented and unpigmented. Pigmented colonies were encapsulated budding spherical yeast, whereas unpigmented colonies were of unencapsulated ovoid budding yeast. In addition to defective melanin production, the unpigmented colony type exhibited defective mating. Genetic analysis by high-resolution multilocus sequence typing revealed that the 2 isolates are genetically identical at 8 unlinked loci tested and that the 2 isolates are both the VGIIa Vancouver Island major genotype. Findings are consistent with expansion of the Vancouver Island outbreak onto the mainland Pacific Northwest region of the United States.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19139515/