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Peer-reviewed veterinary case report

Cuprizone-induced Demyelination in Mouse Brain is not due to Depletion of Copper.

Journal:
ASN neuro
Year:
2022
Authors:
Morgan, Megan L et al.
Affiliation:
Cumming School of Medicine · Canada

Abstract

The demyelinating effects of CPZ are not due to Cu deficiency but are instead consistent with acute toxicity of a CPZ + Cu complex.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/36114624/