Curative effect of autologous platelet-rich plasma on a large cutaneous lesion in a dog.

Abstract

A dorsal tail mass (1 x 1.2 cm) was observed on a 10-year-old castrated male, Shih-tzu dog. A biopsy of the mass was performed and diagnosed histopathologically as a follicular cyst. A necrotic lesion (2.5 x 3 cm) developed at the biopsy site 1 week after sampling and failed to respond to 2 weeks of normal saline cleansing and systemic antibiotic administration. Autologous platelet-rich plasma was applied to the lesion which gradually improved over a 4-week period possibly by a contribution to the secretion of growth hormone, which can accelerate tissue regeneration. This case report suggests that autologous PRP may be beneficial in the management of large skin defects or in delayed wound healing.