Peer-reviewed veterinary case report
Current diagnostic trends in coagulation disorders among dogs and cats.
- Journal:
- The Veterinary clinics of North America. Small animal practice
- Year:
- 2013
- Authors:
- Brooks, Marjory B & Catalfamo, James L
- Affiliation:
- College of Veterinary Medicine · United States
Plain-English summary
When dogs and cats show signs of bleeding, veterinarians need to figure out whether the cause is an injury to blood vessels or a problem with the body's ability to stop bleeding. To do this, they use a mix of general tests and more specific ones that look at different stages of how blood clots. New methods, like flow cytometry and thrombelastography, are being researched to see if they can help diagnose and treat these bleeding issues better, but more studies are needed to confirm their effectiveness.
Abstract
The diagnostic workup to differentiate hemorrhage caused by vascular injury from a systemic hemostatic imbalance typically involves a combination of broad screening tests and specific assays. The characterization of 3 overlapping phases of primary hemostasis, secondary hemostasis, and fibrinolysis provides a simple diagnostic framework for evaluating patients with clinical signs of hemorrhage. New techniques such as flow cytometry, thrombin-generation assays, thrombelastography, and anticoagulant drug monitoring are under investigation for veterinary patients; however, their ability to improve diagnosis or treatment requires further study in clinical trials.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24144095/