Peer-reviewed veterinary case report
How vets diagnose chronic gut problems in dogs
By Allenspach, Karin & Mochel, Jonathan P·Published in Veterinary clinical pathology·2022·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Current diagnostics for chronic enteropathies in dogs.
- Species:
- dog
Plain-English summary
A dog with chronic diarrhea may be suffering from a condition called chronic enteropathy (CE), which can be tricky to diagnose. This condition can be caused by different factors, and vets often need to rule out other issues before determining the best treatment. There are three main types of CE: some dogs respond well to dietary changes, others to antibiotics, and some to steroids. New tests are being developed to help predict which treatment might work best for each dog, making the diagnosis process easier and more effective.
People also search for: dog chronic diarrhea treatment · food-responsive enteropathy in dogs · antibiotic treatment for dog diarrhea
Abstract
Chronic enteropathies (CEs) in dogs describe a group of idiopathic disorders characterized by chronic persistent or recurrent gastrointestinal (GI) signs. Three major subgroups of CE can be identified by their response to treatment: Food-responsive disease (FRD), antibiotic-responsive disease (ARD), and steroid-responsive disease (SRD). The clinical diagnosis of CE is made by exclusion of all other possible causes of chronic diarrhea and includes histologic assessment of intestinal biopsies. The process of diagnosing canine CE can therefore be very time-consuming and expensive, and in most cases, does not help to identify dogs that will respond to a specific treatment. The development of novel diagnostic tests for canine CE has therefore focused on the accuracy of such tests to predict treatment responses. In this article, several novel assays that have the potential to become commercially available will be discussed, such as genetic tests, perinuclear anti-neutrophil cytoplasmic antibodies (pANCA), antibodies against transglutaminase/gliadin, antibodies against E coli OmpC/flagellin, and micro RNAs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34699081/