Peer-reviewed veterinary case report
Dog with Cushing's disease and blood clots treated by surgery
By Teshima, Takahiro et al.Ā·Published in The Journal of veterinary medical scienceĀ·2008Ā·Department of Veterinary Science, JapanĀ·View original on PubMed ā
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Original publication title: Cushing's disease complicated with thrombosis in a dog.
- Species:
- dog
Plain-English summary
An 8-year-old male Beagle with Cushing's disease (a condition causing high cortisol levels) developed blood clots in the large veins and arteries. The dog underwent surgery to remove the pituitary gland and received medication to prevent further clots. After the surgery, his cortisol levels returned to normal, and he showed significant improvement, although one clot remained in the abdominal artery. Sadly, nearly two years later, the dog suddenly had trouble breathing and passed away, with further examination revealing clots in his abdomen and lungs. This case highlights the need for careful monitoring of dogs with Cushing's disease for potential blood clots.
People also search for: Beagle Cushing's disease treatment Ā· dog blood clots symptoms Ā· Cushing's disease surgery outcome
Abstract
Thrombosis is a potential complication of hyperadrenocorticism (HAC) in dogs. An 8-year-old male Beagle diagnosed with pituitary-dependent HAC had complicated with thrombosis in the caudal vena cava and abdominal aorta, which was treated by hypophysectomy and antithrombotic therapy. After hypophysectomy, hypercortisolemia disappeared and the general condition was also significantly improved. Ultrasonography after hypophysectomy revealed that the thrombus remained in the abdominal aorta, but the thrombus in the caudal vena cava had disappeared. However 692 days after the hypophysectomy, the dog had an acute onset of dyspnea and died. Postmortem examination revealed the presence of thrombi in the abdominal aorta and the pulmonary artery. Observations from this case show that HAC dogs must be attention to thrombosis.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18525172/