Peer-reviewed veterinary case report
Causes and management of insulin resistance in diabetic dogs
By Fleeman, Linda & Barrett, Renea·Published in The Veterinary clinics of North America. Small animal practice·2023·Animal Diabetes Australia, Australia·View original on PubMed →
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Original publication title: Cushing's Syndrome and Other Causes of Insulin Resistance in Dogs.
- Species:
- dog
Plain-English summary
A diabetic dog can experience insulin resistance due to several factors, including Cushing's syndrome, being in heat, or obesity. These conditions can lead to unstable blood sugar levels and make managing diabetes more challenging. To help control these issues, veterinarians may use a combination of insulin treatments or recommend surgery to spay female dogs in heat, which can sometimes lead to remission of diabetes. It's important for pet owners to work closely with their vet to find the best treatment plan for their dog's specific situation.
People also search for: dog diabetes treatment · Cushing's syndrome in dogs · insulin resistance in dogs · spaying dog diabetes · managing dog blood sugar levels
Abstract
The most common causes of insulin resistance in diabetic dogs are Cushing syndrome, diestrus, and obesity. Cushing-associated effects include insulin resistance, excessive postprandial hyperglycemia, perceived short duration of insulin action, and/or substantial within-day and/or day-to-day glycemic variability. Successful strategies to manage excessive glycemic variability include basal insulin monotherapy and combined basal-bolus insulin treatment. Ovariohysterectomy and insulin treatment can achieve diabetic remission in about 10% of cases of diestrus diabetes. Different causes of insulin resistance have an additive effect on insulin requirements and the risk of progression to clinical diabetes in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36898861/