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Peer-reviewed veterinary case report

Dog developed neck skin reaction after firocoxib treatment

By Geum, Migyeong et al.·Published in Veterinary medicine and science·2021·Department of Veterinary Internal Medicine, South Korea·View original on PubMed

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Original publication title: Cutaneous adverse drug reaction in a dog following firocoxib treatment.

Species:
dog

Plain-English summary

A 9-year-old female toy poodle developed swelling and pus around her neck just two days after starting firocoxib, a pain medication, for her back issues. The vet found signs of inflammation but decided against a skin biopsy. They stopped the firocoxib and started treatment with cyclosporine, which helped clear up the skin problems. The dog fully recovered in about seven weeks. This case suggests that the dog had an adverse reaction to the firocoxib.

People also search for: dog skin problems after medication · firocoxib side effects in dogs · treatment for dog skin inflammation

Abstract

A 9-year-old intact female toy poodle was presented with oedema around the neck, including pus and cutaneous necrosis, 2 days after starting firocoxib treatment and placement of a cervical collar for intervertebral disc disease. Cytology of the pus revealed predominantly mature neutrophils with fewer macrophages and lymphocytes, indicating sterile inflammation. Although a skin biopsy could have provided more diagnostic information, it was not performed at presentation. Firocoxib treatment was discontinued, and immunosuppressive therapy including cyclosporine was initiated, which significantly alleviated the skin lesions. The dog recovered fully in 7 weeks. The final diagnosis was a possible cutaneous adverse drug reaction to firocoxib based on history, clinical signs and response to therapy.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34021731/