Peer-reviewed veterinary case report
Dog with skin fungal infection cured by cold plasma and stopping
By Classen, Janine et al.·Published in Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·2017·Clinic of Small Animal Medicine, Germany·View original on PubMed →
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Original publication title: Cutaneous alternariosis in an immunocompromised dog successfully treated with cold plasma and cessation of immunosuppressive medication.
- Species:
- dog
Plain-English summary
A 2-year-old male Irish setter was brought in for skin problems, showing multiple bumps, sores, and ulcers on his legs, shoulders, scrotum, ears, and nose. He had been on immunosuppressive medications for inflammatory bowel disease and lymphangiectasia, which likely contributed to a fungal skin infection caused by Alternaria. The vet diagnosed the infection through skin biopsies and cultures. The dog improved significantly after stopping the immunosuppressive drugs, using cold plasma treatment, and applying a topical antifungal medication, achieving complete recovery within eight weeks.
People also search for: dog skin infection treatment · Irish setter skin problems · cold plasma therapy for dogs
Abstract
A cutaneous infection with Alternaria spp. was diagnosed in a 2-year-old male intact Irish setter dog, presenting with multifocal papules, plaques and ulcerations involving all four distal limbs, shoulder blades, scrotum, pinnae and nasal mucous membranes. The dog had been treated for inflammatory bowel disease and lymphangiectasia with immunosuppressive doses of cyclosporine and prednisolone for approximately 3 months. The diagnosis was based on clinical signs, the demonstration of fungal elements within skin biopsies, deep fungal culture and fungal PCR from a formalin-fixed tissue specimen. Complete clinical remission was achieved by tapering and cessation of the immunosuppressive medication, treatment with cold atmospheric-pressure plasma (CAPP) and topical enilconazole within 8 weeks.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28905976/