Peer-reviewed veterinary case report
Dog developed skin and eye reactions after meloxicam treatment
By Niza, Maria M R E et al.·Published in Veterinary dermatology·2007·CIISA/Teaching Hospital of the Faculty of Veterinary Medicine·View original on PubMed →
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Original publication title: Cutaneous and ocular adverse reactions in a dog following meloxicam administration.
- Species:
- dog
Plain-English summary
A 5-year-old mixed-breed dog developed skin and eye problems after being given meloxicam, a common pain medication. The dog's owner noticed unusual reactions, and a skin biopsy showed signs of damage and inflammation that suggested an adverse reaction to the drug. Although the dog had a history of skin allergies, the owner was unaware of any previous drug allergies. After stopping the meloxicam, the dog's symptoms were addressed, highlighting the importance of monitoring for side effects in dogs with a history of skin issues when using NSAIDs.
People also search for: dog skin problems after meloxicam · dog eye problems medication reaction · NSAID side effects in dogs
Abstract
The present report addresses the development of cutaneous and ocular reactions possibly related to meloxicam administration in a dog. Based on clinical signs and absence of laboratory data compatible with the other differential diagnoses considered, the possibility of an adverse drug reaction (ADR) due to meloxicam was considered. Skin biopsy revealed haemorrhage of the superficial and deep dermis, associated with hyperplasia of endothelial cells and epidermal sloughing. Vasculitis in the deep dermis was also noted. Such lesions were considered compatible with an ADR. Although the owner was not aware of any previous allergic reaction to drugs, the animal had a clinical history of atopic dermatitis. Meloxicam is a nonsteroid anti-inflammatory drug (NSAID) in the oxicam family, indicated for the control of inflammation and pain in acute and chronic musculoskeletal disorders in dogs. Although meloxicam is usually well tolerated, the present clinical case represents an alert to practitioners about the potential role of NSAIDS in ADRs in dogs with a history of allergic cutaneous diseases.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17222240/