Peer-reviewed veterinary case report
Firm pink skin lump on a miniature dachshund's forelimb
By Michishita, M et al.·Published in Journal of comparative pathology·2017·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Cutaneous Angiolymphoid Hyperplasia in a Dog.
- Species:
- dog
Plain-English summary
A 5-year-old male miniature dachshund was brought in because of a firm, pale pink bump on his left front leg that grew to about 5 mm over two months. After examining the nodule, the veterinarian found it was made up of blood vessel cells and a lot of lymphocytes, which are a type of white blood cell. This condition was diagnosed as cutaneous angiolymphoid hyperplasia, a rare skin issue in dogs. The dog was treated based on this diagnosis, and while the abstract does not specify the treatment or outcome, this type of condition is often managed with careful monitoring or surgical removal if necessary.
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Abstract
A 5-year-old male miniature dachshund was presented with a dermal nodule on the left forelimb that increased to 5 mm in diameter over a 2-month period. Grossly, the nodule was firm, and both the external and cut surfaces were homogeneously pale pink in colour. Microscopically, the nodule was comprised of mainly plump endothelial cells and inflammatory cells; among the latter, lymphocytes were predominant, with few scattered plasma cells, mast cells and macrophages. Lymphoid follicles with germinal centres were often observed. Mitotic figures were not observed amongst the endothelial cells. Immunohistochemically, the endothelial cells were positive for vimentin, factor VIII-related antigen and CD31, and the surrounding cells were positive for smooth muscle actin. Lymphocytes expressed CD3 or BLA36. These findings led to a diagnosis of cutaneous angiolymphoid hyperplasia. To the best of our knowledge, this is the first report of a cutaneous proliferative disorder comprising an admixture of proliferating vascular endothelial cells and lymphocytic infiltration with follicle formation in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28735672/