Peer-reviewed veterinary case report
Skin tumor with clear cells found on a Bichon-Frise dog's ear
By YASUNO, Kyohei et al.·Published in The Journal of veterinary medical science·2009·Research Institute of Biosciences, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Cutaneous clear cell adnexal carcinoma in a dog: special reference to cytokeratin expression.
- Species:
- dog
Plain-English summary
A 5-year-old male Bichon Frise was brought to the vet with a skin mass near his ear. After examining the growth, the vet found that it was a type of skin cancer called clear cell adnexal carcinoma. This tumor had specific characteristics that were identified through tests, including the presence of certain proteins in the cancer cells. While the abstract does not mention treatment or outcome, it's important for pet owners to discuss options with their veterinarian if they notice unusual growths on their pets.
People also search for: dog skin mass near ear · Bichon Frise skin cancer · clear cell carcinoma treatment for dogs
Abstract
A 5-year-old, male Bichon-Frise dog presented with a cutaneous mass in the basal region of the auricle. Histologically, the cutaneous neoplasm was comprised of lobules with solid cellular proliferation separated by thin fibrous septa. Neoplastic cells varied in size, with moderate to abundant amounts of PAS-positive cytoplasm, large nuclei and prominent nucleoli. Immunohistochemical examinations showed that tumor cells were positive for pan-cytokeratin (CK) (AE1/AE3 and CAM5.2), CK8 and CK18, but negative for pan-CK (KL1), CK7, CK14, CK16 and CK20. Double-labeled immunofluorescence testing indicated that neoplastic cells frequently co-expressed CK and vimentin, suggesting divergent differentiation of tumor cells. Based on these findings, the tumor was diagnosed as canine clear cell adnexal carcinoma.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19959904/