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Peer-reviewed veterinary case report

Skin infection by Setosphaeria turcica in a cat with feline leukemia

By Antonelo, Fábio Antônio et al.·Published in Revista Argentina de microbiologia·2024·Federal University of Technology - Paran&#xe1, Brazil·View original on PubMed

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Original publication title: Cutaneous infection in an immunocompromised domestic cat caused by Setosphaeria turcica (Luttr.) Leonard & Suggs.

Species:
cat

Plain-English summary

A domestic cat with feline leukemia virus (FeLV) was brought in with skin lesions caused by a fungal infection. The cat's weakened immune system made it more susceptible to this infection, which was identified using advanced testing methods. The good news is that the cat responded well to treatment with itraconazole, an antifungal medication, and showed improvement. This case highlights the importance of monitoring skin issues in immunocompromised pets and seeking prompt veterinary care.

People also search for: cat skin infection treatment · feline leukemia virus symptoms · itraconazole for cat fungal infection

Abstract

This is the first report of a cutaneous infection in an immunocompromised domestic cat caused by Setosphaeria turcica. The investigation encompasses an assessment of its virulence factors and susceptibility to antifungal drugs. The isolated strain originated from a domestic cat displaying cutaneous lesions that tested positive for feline leukemia virus (FeLV) infection. Identification procedures employed both microscopic and molecular techniques, with molecular identification relying on ITS DNA sequencing. Enzymatic assays targeting lipase, phospholipase, protease, and keratinase yielded negative results, suggesting the prevalence of alternative virulence mechanisms. Successful treatment of the infection was achieved with itraconazole, and susceptibility testing confirmed its sensitivity to azoles and polyene antifungal drugs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39532595/