Peer-reviewed veterinary case report
Skin nodules linked to coronavirus vasculitis in a cat with FIP
By Cannon, Martha J et al.·Published in Journal of Feline Medicine and Surgery·2005·Oxfordshire Cat Clinic, Larkmead Veterinary Group, Ilges Lane, Cholsey, Oxon OX10 7JP, UK, United Kingdom·View original on Crossref →
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Original publication title: Cutaneous lesions associated with coronavirus-induced vasculitis in a cat with feline infectious peritonitis and concurrent feline immunodeficiency virus infection
- Species:
- cat
Plain-English summary
A 5-year-old male cat with feline infectious peritonitis (FIP) developed multiple nodular skin lesions. These lesions were linked to a severe inflammatory response caused by the virus, which also affected other organs in the cat's body. The veterinarian confirmed the presence of the virus in the skin lesions through specialized testing. Unfortunately, due to the severity of the disease and its complications, the cat's condition was serious, and treatment options were limited.
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Abstract
This report describes a clinical case of feline infectious peritonitis (FIP) with multisystemic involvement, including multiple nodular cutaneous lesions, in a cat that was co-infected with feline coronavirus and feline immunodeficiency virus. The skin lesions were caused by a pyogranulomatous-necrotising dermal phlebitis and periphlebitis. Immunohistology demonstrated the presence of coronavirus antigen in macrophages within these lesions. The pathogenesis of FIP involves a viral associated, disseminated phlebitis and periphlebitis which can arise at many sites. Target organs frequently include the eyes, abdominal organs, pleural and peritoneal membranes, and central nervous tissues, but cutaneous lesions have not previously been reported.
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Search related cases →Original publication on Crossref: https://doi.org/10.1016/j.jfms.2004.12.001