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Peer-reviewed veterinary case report

Cutaneous manifestations of neurological diseases: review of neuro-pathophysiology and diseases causing pruritus.

Journal:
Veterinary dermatology
Year:
2005
Authors:
Gnirs, Kirsten & Prélaud, Pascal
Affiliation:
kgnirs@hotmail.com

Plain-English summary

Sometimes, intense itching in pets doesn't come from skin problems but can be linked to issues in the nervous system or behavior. The nervous system plays a key role in how itching is felt, either making it worse or better. This review talks about different conditions that can cause itching, including inherited or acquired nerve problems and central nervous system disorders like Arnold-Chiari syndrome, seizures, or tumors. Understanding these connections can help veterinarians figure out whether the itching is due to a skin issue or something neurological.

Abstract

Pruritus does not always originate from stimulation to the skin associated with primary dermatological disorders. It may be caused by neurological or behavioural disorders. The essential role of the nervous system in the control (enhancement and inhibition) of pruritus and its pathophysiology are presented. In order to allow differentiation between dermatological and neurological disorders, inherited or acquired peripheral neuropathies and central nervous disorders (Arnold-Chiari syndrome, seizure-related disorders, central nervous system tumours) that may induce itch are discussed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15960625/