Peer-reviewed veterinary case report
Risk factors for skin mast cell tumors in dogs by breed and size
By White, Carrie R et al.·Published in Journal of the American Animal Hospital Association·2011·Department of Internal Medicine, United States·View original on PubMed →
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Original publication title: Cutaneous MCTs: associations with spay/neuter status, breed, body size, and phylogenetic cluster.
- Species:
- dog
Plain-English summary
Certain dog breeds, especially spayed females, have a higher risk of developing mast cell tumors (MCT), which are a type of skin cancer. This study found that Boxers, Labrador Retrievers, Pugs, and Golden Retrievers are particularly at risk, along with larger breeds. Spayed female dogs had over four times the risk compared to intact females. If you have a dog in one of these breeds, it's important to keep an eye on their skin for any unusual lumps or bumps and consult your veterinarian if you notice anything concerning.
People also search for: dog skin cancer symptoms · mast cell tumor in Boxers · spayed female dog cancer risk · Labrador Retriever skin lumps · golden retriever mast cell tumor signs
Abstract
Certain breeds are known to be overrepresented among mast cell tumor (MCT) patients, but other risk factors have not been evaluated. This study presents results from a case-control study of 252 dogs with grade 2 or grade 3 cutaneous MCT. Increased risk for MCT development was found in spayed females (adjusted odds ratio [OR], 4.11), boxers (adjusted OR, 6.09), Labrador retrievers (adjusted OR, 3.95), pugs (adjusted OR, 3.17), golden retrievers (adjusted OR, 2.12), the mastiff and terrier phylogenetic cluster (adjusted OR, 3.19), and breeds classified as large (adjusted OR, 2.10) or giant (adjusted OR, 5.44). Additional studies are needed to evaluate the role of these and other potential risk factors in MCT development.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21498594/