Peer-reviewed veterinary case report
Cyclosporine helps heal anal furunculosis in 26 dogs
By Hardie, R J et al.·Published in The Journal of small animal practice·2005·The Royal Veterinary College·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Cyclosporine treatment of anal furunculosis in 26 dogs.
- Species:
- dog
Plain-English summary
A group of 26 dogs with anal furunculosis (painful sores around the rear end) were treated with cyclosporine, an immunosuppressive medication. After an average of about 9 weeks, 18 dogs completely healed, while 7 showed improvement but still had some lesions. Unfortunately, 9 dogs had a recurrence of their symptoms later on. Although many dogs experienced side effects from the medication, none needed to stop treatment. Overall, cyclosporine was effective for most dogs, but some may need additional surgery or ongoing treatment.
People also search for: dog anal furunculosis treatment · cyclosporine side effects in dogs · dog rear end sores healing time
Abstract
OBJECTIVES: To evaluate the effect of cyclosporine on anal furunculosis lesions in 26 dogs. METHODS: Lesions were graded as mild in 11 dogs, moderate in eight and severe in seven. Each dog was treated with approximately 4 mg/kg cyclosporine orally every 12 hours until the lesions resolved or showed no further improvement. Residual lesions were resected surgically. RESULTS: Eighteen dogs (69 per cent) experienced complete resolution, seven (27 per cent) improved but had residual lesions and one (4 per cent) showed no improvement. The mean duration of treatment until resolution or no further improvement was 8.8 weeks (range four to 24 weeks). Nine dogs (35 per cent) experienced recurrence. Six were from the group that had shown complete resolution and three were from the group that had surgery. Fifteen dogs (58 per cent) developed side effects to cyclosporine, although none required treatment to be discontinued. Mean duration of follow-up was 6.8 months (range one to 20 months). CLINICAL SIGNIFICANCE: Cyclosporine was effective at resolving or reducing anal furunculosis lesions in 25 of 26 dogs (96 per cent). However, residual or recurrent lesions remain a potential problem, and surgical resection or long-term cyclosporine treatment may be necessary in some dogs.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15682733/