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Peer-reviewed veterinary case report

Cystine and urate bladder stones in dogs often show on X-rays

By Andrews, Camille et al.·Published in Journal of the American Veterinary Medical Association·2024·View original on PubMed

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Original publication title: Cystine and urate cystoliths in dogs are frequently visible on radiographs prior to surgical or nonsurgical removal.

Species:
dog

Plain-English summary

A study found that many dogs with cystine and urate stones (types of bladder stones) showed these stones on X-rays before any treatment. Out of 331 dogs, 85% of those with urate stones and 92% with cystine stones had visible stones on their radiographs. This is important because it helps veterinarians decide on the best treatment, including whether a special diet might be effective. Knowing that these stones can be seen on X-rays can lead to better management and prevention strategies for dogs prone to these types of stones.

People also search for: dog bladder stones treatment · cystine stones in dogs · urate stones in dogs · dog diet for bladder stones

Abstract

OBJECTIVE: To investigate the frequency at which cystine and urate cystoliths (stones) are visible on radiographs prior to surgical or nonsurgical retrieval. METHODS: Records of client-owned dogs (n = 331) were analyzed between January 2019 and December 2023 for cystoliths submitted for stone analysis after surgical removal or nonsurgical retrieval. Records were analyzed for cystolith type; when cystine or urate stones were identified, records were analyzed for signalment, procedure, presence of mineral opaque cystoliths on pre-procedural radiographs, urine pH and crystalluria, history of previous cystoliths, prior prescription diet attempt, recurrence, and genetic, congenital and acquired comorbidities. Descriptive statistics were generated after data collection. RESULTS: 31 of 331 (9%) were cystine stones, 49 of 331 (15%) were urate, and 1 of 331 (0.3%) was a mix of urate and cystine. When radiographs were taken prior to stone removal, 24 of 28 (85%) of urate, 24 of 26 (92%) of cystine, and 1 of 1 (100%) of urate/cystine were visible on radiographs. CONCLUSIONS: Cystine and urate stones are visible on survey radiography at a high frequency in dogs. CLINICAL RELEVANCE: While cystine and urate stones have been historically designated as radiolucent, they are frequently radiopaque on radiographs. Radiopacity is commonly used as one of the criterion to determine whether a dissolution or prevention diet is an appropriate management technique, particularly when determination of the stone type has yet to be performed. As a result, these findings may prompt clinicians to investigate other patient-specific factors before a specific dietary recommendation is made.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39059429/