Peer-reviewed veterinary case report
Bladder infection with E. coli in diabetic Miniature Schnauzer
By J. P. R. Amunategui et al.·Published in BMC Veterinary Research·2025·View original on Semantic Scholar →
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Original publication title: Cystitis glandularis due to Escherichia coli infection in a diabetic Miniature Schnauzer: a case report
- Species:
- dog
Plain-English summary
A 12-year-old Miniature Schnauzer with diabetes was brought in for frequent urination, painful urination, and blood in the urine. Despite treatment, his symptoms didn't improve, so the vet performed surgery to examine his bladder. They found abnormal growths and signs of infection caused by E. coli bacteria. After starting antibiotics and pain relief, the dog's symptoms improved significantly, and he eventually recovered completely.
People also search for: dog blood in urine treatment · Miniature Schnauzer urinary tract infection · diabetes in dogs symptoms
Abstract
Lower urinary tract disease is a common clinical condition in dogs, usually presenting with dysuria, pollakiuria and haematuria. Diabetes mellitus is a predisposing factor for urinary tract infection in both humans and dogs and does not necessarily present with clinical signs. In this case report, we describe for the first time a case of cystitis glandularis in a dog with diabetes mellitus, associated with Escherichia coli urinary tract infection. A 12 year old 9.2-kg (20.2-lb) castrated male Miniature Schnauzer with diabetes mellitus, was referred because of continued dysuria, pollakiuria and hematuria without a satisfactory response to treatment. The abdominal ultrasound revealed an irregular increase in mural thickness of the bladder, together with multiple immobile structures, apparently originating on the dorsal surface, of varied longitudinal diameters, with a convex hyperechogenic interface with an acoustic shadow. It was decided to perform a surgical cystotomy, which revealed that the surface of the urothelium showed dark hemorrhagic staining and multiple nodular structures, which were relatively hard to palpate. Histological examination of the bladder wall revealed hyperplastic urothelial epithelium, submucosal glandular formations with well differentiated mature cells and a chorion with signs of edema, concluding a diagnosis of cystitis glandularis. Bacteriological culture of the urothelium and urine revealed Escherichia coli infection. After initiation of antibiotic therapy and pain management, the dog's clinical signs improved markedly until complete remission of the bladder lesions. Although there have been few reports of this clinical presentation in veterinary medicine, two in cats and one in a female schnauzer, this is the first reported case of cystitis glandularis associated with urinary tract infection due to Escherichia coli. The importance of bacteriological and histopathological studies in the diagnosis of urinary tract pathologies should be emphasized.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/39825317