Peer-reviewed veterinary case report
Parasites found in dog spinal fluid linked to unique mouse-virulent
By Borges-Silva, Waléria et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2021·Department of Veterinary Anatomy, Brazil·View original on PubMed →
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Original publication title: Cytologic detection ofin the cerebrospinal fluid of a dog and in vitro isolation of a unique mouse-virulent recombinant strain.
- Species:
- dog
Plain-English summary
A dog with neurological problems was found to have parasites in its cerebrospinal fluid, which led to severe illness and ultimately euthanasia. The diagnosis was made through a special examination of the fluid, which revealed the presence of Toxoplasma gondii, a parasite that can cause serious health issues. This case highlights the importance of testing cerebrospinal fluid in dogs showing neurological symptoms. Unfortunately, the dog did not survive, but the findings could help in diagnosing similar cases in the future.
People also search for: dog neurological problems · dog cerebrospinal fluid test · Toxoplasma gondii in dogs
Abstract
Parasites resemblingorwere detected by cytologic examination of cerebrospinal fluid (CSF) from a dog with neurologic disease. The dog became severely ill and was euthanized. Canine tissue homogenates were used for direct parasite isolation in cell culture, bioassay in 2 mouse lineages, and PCR.was isolated in monkey kidney cells, and species identity was confirmed by PCR. Inoculated parasites were highly virulent for mice, which developed clinical signs and were euthanized immediately. PCR-RFLP forusing the cultured isolate (TgDgBA22) was conducted with 12 genetic markers, and a unique recombinant strain was identified. Detection ofby CSF cytology, although described in humans, had not been reported previously in dogs, to our knowledge, and was crucial for the diagnosis of toxoplasmosis in the examined dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33719752/