Peer-reviewed veterinary case report
How well liver needle tests find inflammation in dogs
By Weiss, Douglas J. et al.·Published in Veterinary Clinical Pathology·2001·View original on Crossref →
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Original publication title: Cytologic Evaluation of Inflammation in Canine Liver Aspirates
- Species:
- dog
Plain-English summary
A study looked at how well liver aspiration tests can detect inflammation in dogs with liver disease. The tests were found to be very effective, especially for conditions like suppurative hepatitis and chronic active hepatitis, with nearly perfect sensitivity and specificity. However, the tests were not as reliable for identifying lymphocytic hepatitis. This means that if your dog has liver issues, a liver aspiration test could be a good option for diagnosing certain types of inflammation, but it might not catch all cases.
People also search for: dog liver disease symptoms · canine liver aspiration test results · dog hepatitis treatment
Abstract
Abstract: Liver aspiration cytology has been used routinely for more than a decade for the evaluation of canine and feline liver disease. However, the value of liver cytology in detecting inflammatory liver disease is poorly defined. We retrospectively reviewed 51 canine liver cytology reports and compared the conclusions with those from concurrent surgical biopsy reports. Overall sensitivity of cytology for diagnosis of inflammatory liver disease was 93% and specificity was 96%. For suppurative hepatitis (n = 14), the sensitivity of cytologic diagnosis was 100% and the specificity was 95%. For chronic active hepatitis (n = 13), the sensitivity of cytologic diagnosis was 100% and the specificity was 93%. For lymphocytic hepatitis (n = 3), the sensitivity of cytologic diagnosis was 33% and the specificity was 100%. We conclude that canine liver aspiration cytology is a highly sensitive test for the detection of suppurative and chronic active inflammation; however, it is insensitive for the detection of lymphocytic hepatitis.
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/j.1939-165x.2001.tb00431.x