Peer-reviewed veterinary case report
Pancreatic fine-needle aspiration in 92 dogs diagnostic results
By Cordner, Amy P et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2015·Veterinary Clinical Sciences Department·View original on PubMed →
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Original publication title: Cytologic findings and diagnostic yield in 92 dogs undergoing fine-needle aspiration of the pancreas.
- Species:
- dog
Plain-English summary
A group of 92 dogs underwent a procedure called fine-needle aspiration (FNA) to help diagnose pancreatic disease, which can be tricky due to vague symptoms. The results showed that FNA provided a clear diagnosis in about 74% of the cases, and when compared to other tests, the findings matched up well in most instances. While there were some adverse events, these mostly occurred in dogs that already had serious health issues or were undergoing other procedures. Overall, pancreatic FNA appears to be a safe and effective way to diagnose pancreatic problems in dogs.
People also search for: dog pancreatic disease symptoms · fine-needle aspiration pancreas dog · dog pancreatic cancer diagnosis
Abstract
The diagnosis of pancreatic disease in small animal veterinary patients is complicated by nonspecific clinical signs and the limitations of diagnostic testing. Pancreatic cytology is a potential diagnostic tool, but safety and diagnostic yield are not well characterized in large patient cohorts. We hypothesized that pancreatic fine-needle aspiration (FNA) in dogs would frequently generate diagnostic-quality samples and subsequent adverse medical events would be uncommon. Ninety-two client-owned dogs undergoing pancreatic FNA for clinical diagnostic evaluation were identified retrospectively by a computer search for pancreatic cytology submissions. Archived slides were reviewed by a single board-certified clinical pathologist using a predetermined descriptive scheme. Medical records were reviewed for adverse events 48 hr following FNA, for concurrent procedures and diagnosis in patients with adverse events and for histology results. Diagnostic yield was calculated as the % cases in which a cytologic diagnosis could be achieved; correlation with histology or other confirmatory testing was determined when possible. Diagnostic yield was 73.5%, and the major pathologic process identified cytologically correlated with confirmatory testing in 10 out of 11 cases. There were 7 adverse events, all in dogs with significant comorbidities or undergoing other invasive procedures. Pancreatic FNA in dogs has a good diagnostic yield and a low rate of clinical complications in a large case series of dogs. Correlation of cytology and histology results was high in a limited number of cases.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25776547/