Peer-reviewed veterinary case report
Cat with stomach tumor causing vomiting diagnosed by biopsy and gene
By Morini, M et al.·Published in Journal of comparative pathology·2011·Department of Veterinary Public Health and Animal Pathology, Italy·View original on PubMed →
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Original publication title: Cytological, immunohistochemical and mutational analysis of a gastric gastrointestinal stromal tumour in a cat.
- Species:
- cat
Plain-English summary
A 10-year-old female domestic shorthair cat was brought to the vet because she had been vomiting repeatedly. During the examination, the vet found a mass in her stomach and performed surgery to remove it. Tests showed that the mass was a low-grade malignant tumor called a gastrointestinal stromal tumor (GIST), which is rare in cats. The vet confirmed the diagnosis with special staining techniques and found a genetic mutation similar to those seen in human cases. The cat's treatment plan would likely involve monitoring and possibly further treatment based on her recovery.
People also search for: cat vomiting · cat stomach tumor treatment · gastrointestinal stromal tumor in cats · cat cancer symptoms · cat surgery recovery
Abstract
Gastrointestinal stromal tumours (GISTs) represent a distinctive group of primary mesenchymal tumours of the gastrointestinal tract identified immunohistochemically by expression of CD117. A 10-year-old neutered female domestic shorthair cat with a history of recurrent vomiting was examined. The presence of a gastric mass was recognized and a laparotomy was performed. Cytological examination was consistent with a low-grade malignant mesenchymal tumour and histopathological investigation suggested myogenic differentiation of tumour cells. The diagnosis of GIST was confirmed by immunohistochemical expression of CD117. Sequence analysis of the KIT gene identified a deletion in exon 11. The same mutation is found often in human GISTs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21333305/