Peer-reviewed veterinary case report
Lymph node tests predict survival in dogs with mast cell tumors
By Krick, E L et al.·Published in Veterinary and comparative oncology·2009·Department of Clinical Studies, United States·View original on PubMed →
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Original publication title: Cytological lymph node evaluation in dogs with mast cell tumours: association with grade and survival.
- Species:
- dog
Plain-English summary
A group of 152 dogs with mast cell tumors (a type of skin cancer) had their lymph nodes checked to see if the cancer had spread. The study found that dogs with stage II tumors, which are more advanced, had a much shorter survival time compared to those with stage I tumors, living on average only about 8 months versus over 6 years. Additionally, dogs with grade III tumors were more likely to have stage II disease. This information can help veterinarians assess the severity of the cancer and guide treatment options for better outcomes.
People also search for: dog mast cell tumor survival · lymph node cancer in dogs · mast cell tumor treatment options
Abstract
The purpose of this retrospective cohort study is to describe the association of cytological assessment of lymph node metastasis with survival and tumour grade in dogs with mast cell tumours. Regional lymph node aspirates of 152 dogs diagnosed with a mast cell tumour were reviewed and classified according to specific cytological criteria for staging. 97 dogs (63.8%) had stage I tumours, and 55 (36.2%) had stage II tumours. Stage II dogs had a significantly shorter survival time than dogs with stage I disease (0.8 and 6.2 years, respectively; P < 0.0001). Dogs with grade III mast cell tumours were more likely to have stage II disease (P = 0.004). These results suggest that cytological evaluation of lymph nodes in dogs with mast cell tumours provides useful and valuable clinical information, and the results correlate with tumour grade and outcome thus providing a practical and non-invasive method for staging.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19453367/