Peer-reviewed veterinary case report
Cytomegaloviral hypophysitis in a simian immunodeficiency virus-infected rhesus macaque (Macacca mulatta).
- Journal:
- Journal of medical primatology
- Year:
- 2017
- Authors:
- Berg, Melissa R et al.
- Affiliation:
- Southwest National Primate Research Center at the Texas Biomedical Research Institute · United States
Abstract
Rhesus macaques experimentally infected with Simian Immunodeficiency Virus (SIV) experience immunosuppression and often opportunistic infection. Among the most common opportunistic infections are rhesus cytomegalovirus (RhCMV), a ubiquitous betaherpesvirus that undergoes continuous low-level replication in immunocompetent monkeys. Upon SIV-mediated immunodeficiency, RhCMV reactivates and results in lesions in numerous organ systems including the nervous and reproductive systems. We report the first case of cytomegaloviral hypophysitis in a SIV-immunocompromised rhesus macaque.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28671330/