Peer-reviewed veterinary case report
Rare peritoneal deciduoid mesothelioma in a 10-year-old female dog
By Morini, M et al.·Published in Veterinary pathology·2006·Dipartimento di Sanità, Italy·View original on PubMed →
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Original publication title: Deciduoid peritoneal mesothelioma in a dog.
- Species:
- dog
Plain-English summary
A 10-year-old female dog was diagnosed with a rare type of cancer called deciduoid peritoneal mesothelioma, which affects the lining of the abdomen. The dog had multiple small, whitish-gray nodules in her abdominal cavity. Tests showed that the tumor cells had specific characteristics that confirmed they originated from the mesothelium, the tissue lining the abdomen. Unfortunately, this type of cancer is quite serious, and the treatment options for such rare tumors can be limited.
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Abstract
Deciduoid mesothelioma is a rare variant of epithelial mesothelioma, up to now only described in human pathology, which bears remarkable cytomorphologic resemblance to the endometrium of pregnancy, termed decidua. A case of peritoneal mesothelioma with deciduoid features in a 10-year-old, female dog is reported. Multiple whitish-gray nodules (1-5 mm in diameter) in parietal peritoneum and mesentery were histologically composed of large, proliferating, polygonal or ovoid cells with an abundant eosinophilic, glassy cytoplasm. Immunohistochemical evaluation indicated that the neoplastic cells coexpressed cytokeratin and vimentin with strong and diffuse cytoplasmic staining, and ultrastructural analysis showed long and slender mesothelial-type microvilli; these findings confirmed the mesothelial origin of the tumor.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16537940/