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Peer-reviewed veterinary case report

Deep cornea transplant in dogs using big-bubble technique

By Kim, Soohyun et al.·Published in Journal of veterinary science·2016·Department of Veterinary Clinical Science, South Korea·View original on PubMed

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Original publication title: Deep anterior lamellar keratoplasty of dog eyes using the big-bubble technique.

Species:
dog

Plain-English summary

A group of three dogs underwent a special eye surgery called deep anterior lamellar keratoplasty (DALK) using a technique known as the big-bubble technique to treat corneal issues. After the surgery, the dogs were given antibiotic drops and a special ointment to help with healing. While the central part of the transplanted cornea remained clear, some haze developed around the edges, but the dogs' vision responses were normal. By the end of the study, the transplanted corneas showed mostly healthy structures, indicating that this surgical method can be effective for dogs needing corneal transplants.

People also search for: dog eye surgery · corneal transplant for dogs · big-bubble technique dog eyes · dog eye haze treatment

Abstract

This study was conducted to establish the feasibility of corneal transplantation using the big-bubble technique (BBT) to perform deep anterior lamellar keratoplasty (DALK) in three dogs. After the cornea was trephined 750 µm, 4 mL of air was injected, and the blanched stroma was removed to expose Descemet's membrane (DM). The donor corneal button, which was gently stripped off the DM, was sutured onto the bare DM of the recipient cornea. The dogs received topical antibiotics every 6 h for 7 days and 2% cyclosporine ointment every 12 h for 1 month. The eyes were examined post-operatively at 7, 14, 21, 28 and 150 days. The central portion of the transplanted cornea stayed transparent while corneal haze developed around the transplanted margin. Menace response was normal even though the transplanted cornea was edematous until 3 weeks after surgery. A marginal haze was rarely observed between the donor and recipient corneas at 150 days after the operation. A spotted haze developed in the central part of the deep stroma near the DM. Upon histopathological examination, the stroma and epithelium of the donor cornea had normal structures. Corneal transplantation using DALK with BBT can be performed in dogs preserving the healthy endothelium.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26645335/