Peer-reviewed veterinary case report
Immunotherapy with dust mite allergen did not improve itching
By Willemse, T et al.·Published in Veterinary journal (London, England : 1997)·2009·Department of Clinical Sciences of Companion Animals, Netherlands·View original on PubMed →
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Original publication title: Dermatophagoides farinae-specific immunotherapy in atopic dogs with hypersensitivity to multiple allergens: a randomised, double blind, placebo-controlled study.
- Species:
- dog
Plain-English summary
A group of 25 dogs with atopic dermatitis (a skin condition caused by allergies) were tested for their reactions to a common dust mite allergen and other allergens. They received either a special treatment aimed at reducing sensitivity to the dust mite or a placebo. After several months of treatment, both groups showed similar levels of itching and skin problems, indicating that the dust mite-specific treatment did not help control their symptoms. This suggests that dogs with multiple allergies may need a more personalized approach to their allergy treatment.
People also search for: dog skin allergies treatment · atopic dermatitis in dogs · dust mite allergy in dogs
Abstract
A randomised, placebo-controlled, double blind study was conducted on 25 dogs that had atopic dermatitis, together with skin test reactivity and elevated serum IgE to Dermatophagoides farinae (Df) and at least one additional allergen. Dogs were treated with either a Df-restricted immunotherapy solution (n=14) or a placebo (n=11) and evaluated 6 weeks and 3, 5, 7 and 9 months after the initiation of treatment using a clinical scoring system (SASSAD) and pruritus analogue scale scores. The Df-restricted solution and the placebo had an equal effect on both pruritus and the skin manifestations (P>0.05). The results of this study indicate that in dogs with atopic dermatitis based on hypersensitivity to environmental allergens in addition to D. farinae, Df-restricted immunotherapy is insufficient to control the disease. Consequently, a solution for allergen-specific immunotherapy should remain customised.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18653361/