Peer-reviewed veterinary case report
Deslorelin implant for hair loss in male Keeshond dogs
By Layne, Elizabeth A & Richmond, Renee V·Published in Journal of the American Animal Hospital Association·2018·From the Department of Pathobiological Sciences and the Department of Medical Sciences·View original on PubMed →
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Original publication title: Deslorelin Implant Treatment for Hair Cycle Arrest (Alopecia X) in Two Intact Male Keeshonden.
- Species:
- dog
Plain-English summary
Two male Keeshonden were brought in for hair loss on their bodies, which had been getting worse for over two years. They were diagnosed with a condition called hair cycle arrest (alopecia X), where the hair stops growing but the skin is otherwise healthy. A single deslorelin acetate implant was given under the skin, and within about three and a half months, both dogs experienced significant hair regrowth that lasted for at least 14 months. This treatment seems to be a safe and effective option for this type of hair loss in male Keeshonden.
People also search for: Keeshond hair loss treatment · alopecia X in dogs · deslorelin for dog hair regrowth
Abstract
Alopecia in dogs occurs secondary to a variety of underlying inflammatory and noninflammatory conditions. Hair cycle arrest (alopecia X) is a noninflammatory alopecia that is frustrating to diagnose and treat due to lack of understanding of disease pathogenesis. A variety of therapies for hair cycle arrest have been described with inconsistent efficacy in different dog breeds and sexes; no definitive treatment is available. This report describes the use of a deslorelin acetate implant in two sexually intact adult male keeshonden, both diagnosed with hair cycle arrest. The dogs had progressive alopecia of the trunk that spared the head and distal limbs present for at least 2 yr. Diagnosis of hair cycle arrest was made based on clinical features, dermatohistopathology, and lack of systemic abnormalities. Treatment with a single subcutaneous 4.7 mg deslorelin acetate implant resulted in profuse hair regrowth within 3.5 mo that endured for at least 14 mo. Deslorelin implantation is a management option that is safe, affordable, and appears effective for sexually intact male keeshonden with hair cycle arrest.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29757666/