Peer-reviewed veterinary case report
Dog with low adrenal hormone treated successfully with DOCP injections
By Van Zyl, M & Hyman, W B·Published in Journal of the South African Veterinary Association·1994·Department of Medicine·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Desoxycorticosterone pivalate in the management of canine primary hypoadrenocorticism.
- Species:
- dog
Plain-English summary
A 3-year-old female Cocker Spaniel was diagnosed with primary hypoadrenocorticism, a condition where the adrenal glands don't produce enough hormones. The dog initially received oral fluorocortisone, but it didn't effectively manage her electrolyte levels. Switching to an injectable treatment called desoxycorticosterone pivalate (DOCP) every 28 days helped keep her sodium and potassium levels normal for five years. The side effects were minimal, making this a successful long-term treatment option for her condition.
People also search for: Cocker Spaniel adrenal disease treatment · dog low sodium potassium symptoms · hypoadrenocorticism in dogs treatment
Abstract
Primary hypoadrenocorticism in dogs may be poorly responsive to oral fluorocortisone treatment. Desoxycorticosterone pivalate is a suggested alternative treatment in these and all other cases of hypoadrenocorticism. Primary hypoadrenocorticism was diagnosed in a 3-year-old Cocker Spaniel bitch. Treatment with oral fluorocortisone at a dose rate of 0.13 mg 5 kg-1 d-1 was ineffective at maintaining serum electrolyte concentrations within normal limits. Administration of DOCP at a dose of 1.6-2.2 mg kg-1 intramuscularly every 28 d over a 5-year period, successfully maintained normal serum sodium and potassium concentrations. Side-effects encountered were minimal and were dose- or disease-related.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7595920/