Peer-reviewed veterinary case report
Feline calicivirus causing paw and mouth disease in cats
By Andrea Palombieri et al.·Published in Animals·2022·Department of Veterinary Medicine, Università degli Studi di Teramo, 64100 Teramo, Italy, CH·View original on DOAJ →
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Original publication title: Detection and Characterization of Feline Calicivirus Associated with Paw and Mouth Disease
- Species:
- cat
Plain-English summary
A 7-year-old cat developed paw and mouth disease due to an infection with feline calicivirus (FCV), which can cause various symptoms, including upper respiratory issues. Another cat in the same household was also infected but showed no symptoms. Tests confirmed the presence of FCV in both cats, and researchers found that the virus strains were genetically different from those typically associated with severe disease. While the virus was resistant to low pH, it was sensitive to certain treatments. The affected cat likely received supportive care, but specific treatment details were not provided.
People also search for: cat paw and mouth disease · feline calicivirus symptoms · treatment for cat mouth sores
Abstract
Feline calicivirus (FCV) infection in cats can led to several diverse clinical presentations, ranging from mild upper respiratory signs to virulent systemic disease. Herein, we report a paw and mouth disease case in a 7-year-old household cat due to an FCV infection. An asymptomatic cat living in the same household was also infected with FCV. Clinical and pathological investigations were combined with the molecular and phenotypical characterization of the FCV strains. The RNA of the FCV was detected using qualitative and quantitative reverse transcription (RT)-PCR assays, and FCV antigen was confirmed by immunohistochemistry. After the whole genome analysis, the strains detected in the two cats appeared to be genetically diverse from FCVs previously detected in association with paw and mouth disease and with virulent systemic disease. Interestingly, the isolates obtained in this study were resistant to low pH conditions and slightly susceptible to bile salts, but they were susceptible to a trypsin treatment, revealing a phenotype pattern that is different from that which has been observed for respiratory FCVs.
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Search related cases →Original publication on DOAJ: https://doi.org/10.3390/ani13010065