Peer-reviewed veterinary case report
Detection and genetic characterization of hepatitis E virus (HEV) genotype 3 subtype c in wild boars in Italy.
- Journal:
- Archives of virology
- Year:
- 2016
- Authors:
- Di Profio, Federica et al.
- Affiliation:
- Faculty of Veterinary Medicine · Italy
Abstract
Hepatitis E virus (HEV) was detected in stools collected from wild boars in Italy, with an overall prevalence of 1.5 % (3/196). The sequence of a ~3.0-kb portion at the 3' end of the genome of one such strain, HEV/WB/P6-15/ITA, was determined. In the full-length ORF2, which encodes the capsid protein, the virus was genetically closest to wild boar and human HEV strains currently classified as genotype 3 subtype c. Interestingly, the 3' end of ORF2 of the WB/P6-15/ITA matched the 340-nucleotide (nt) sequence (94.0 % nt identity) of the human strain PeGe, identified in 2015 from a patient with acute hepatitis E in Genoa, Italy, suggesting that similar HEV strains are circulating in the same geographical setting in humans and animals.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27393602/