Peer-reviewed veterinary case report
Sapoviruses found in young dogs with acute gastroenteritis
By Bodnar, Livia et al.·Published in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases·2016·Department of Veterinary Medicine, Italy·View original on PubMed →
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Original publication title: Detection and molecular characterization of sapoviruses in dogs.
- Species:
- dog
Plain-English summary
A group of young dogs with diarrhea was tested for sapoviruses, a type of virus that can cause gastroenteritis. Out of 320 dogs with symptoms, 7 tested positive for the virus, while none of the healthy dogs showed any signs of infection. The researchers found that these sapoviruses had unique genetic features, suggesting they may be different from other known strains. This study highlights the potential for sapoviruses to affect dogs, but more research is needed to understand their impact on canine health.
People also search for: dog diarrhea causes · sapovirus in dogs · puppy gastroenteritis treatment
Abstract
Caliciviruses are important human and animal pathogens. Novel caliciviruses have been identified recently in dogs, raising questions about their pathogenic role and concerns regarding their zoonotic potential. By screening stool samples of young or juvenile dogs using RT-PCR assays, sapoviruses (SaVs) were found in 7/320 (2.2%) samples of animals with acute gastroenteritis while they were not detected in healthy animals (0/119). The sequence of a nearly 3kb portion at the 3' end of the genome, encompassing the RNA-dependent RNA polymerase (RdRp), the capsid region (ORF1) and the ORF2 were determined for three strains. A distinctive genetic feature in canine SaVs was a 4-nucleotide (nt) interval between the ORF1 and ORF2. Two strains (Bari/4076/07/ITA and Bari/253/07/ITA) were very closely related in the RdRp and capsid regions to the strain AN210D/09/USA (90.4-93.9% nt), while strain Bari/5020/07/ITA displayed only 71.0-72.0% nt identity to this group of canine SaVs and 76.0% to strain AN196/09/USA. Overall, these findings indicate that the canine SaVs detected in Italy may represent distinct capsid types, although all currently known SaVs segregate into the novel proposed genogroup, tentatively named as GXIII.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26658065/