Peer-reviewed veterinary case report
Molecular detection of Rangelia vitalii infection in dogs from Parana
By Silva, Bianca Ressetti da et al.·Published in Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria·2019·Programa de Pó·View original on PubMed →
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Original publication title: Detection molecular of Rangelia vitalii in dogs from Parana State, Southern Brazil.
- Species:
- dog
Plain-English summary
Three dogs in Brazil were found to have a blood infection caused by a parasite called Rangelia vitalii. These dogs showed symptoms like tiredness, loss of appetite, and bleeding. Tests revealed severe anemia and low platelet counts, and their blood samples confirmed the presence of the parasite. Treatment details weren't specified, but addressing the anemia and managing the infection would be critical for recovery.
People also search for: dog tiredness and bleeding · dog blood infection treatment · Rangelia vitalii symptoms in dogs
Abstract
Rangelia vitalii infects erythrocytes, leukocytes and endothelial cells of dogs. The present study aimed to report the molecular detection confirmed by sequencing of R. vitalii in the state of Paraná, as well as describe the clinical, hematological and biochemical alterations of the infected dogs. Three sick dogs from the metropolitan area of Curitiba, PR, Brazil, underwent a physical exam, and laboratory tests included hematology, biochemistry, polymerase chain reaction (PCR), and gene sequencing. Clinical signs included apathy, anorexia, and hemorrhage. Intra-erythrocytic and extracellular piroplasms were found on peripheral blood smears from all three dogs. Blood samples from these animals were positive for Babesia sp. by PCR targeting 18S rRNA. PCR products from all three dogs were sequenced, and BLAST analysis showed that the PCR-generated sequences were highly homologous with those of R. vitalii previously reported. Hematologic findings included severe anemia, shift of neutrophils to the regenerative left, and thrombocytopenia. Serum urea levels were increased in all three dogs, and direct bilirubin levels were elevated in one dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30540115/