Peer-reviewed veterinary case report
Detecting Babesia gibsoni in dogs using P50 antibody test
By Hirose, Yoshino et al.·Published in The Journal of veterinary medical science·2009·Department of Veterinary Parasitological Diseases, Japan·View original on PubMed →
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Original publication title: Detection of Babesia gibsoni by reaction of phage display single chain antibodies with P50 proteins.
- Species:
- dog
Plain-English summary
A dog infected with Babesia gibsoni, a parasite that can cause serious illness, often shows symptoms like fever, weakness, and anemia. Traditional blood tests can miss low levels of this infection, making it hard for vets to diagnose. Researchers developed a new test using a special antibody that can more accurately identify the parasite in blood samples. This new method helps vets detect Babesia gibsoni more reliably, which could lead to quicker and more effective treatment for affected dogs.
People also search for: dog Babesia gibsoni symptoms · how to test for Babesia in dogs · treatment for dog piroplasmosis
Abstract
Babesia gibsoni (B. gibsoni) is a tick-borne hemoprotozoan parasite, which causes piroplasmosis in dogs. Diagnosis of canine babesiosis is commonly carried out using Giemsa-stained thin blood smears. However, at low levels of infection, it is difficult to detect Babesia organisms by observation of Giemsa-stained thin blood smears. We constructed a monoclonal phage display single chain antibody (scFv) against a B. gibsoni merozoite antigen, P50 protein. Intraerythrocytic B. gibsoni organisms are clearly stained using this antibody. The monoclonal scFv facilitated the detection of B. gibsoni organisms in canine blood samples.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19721374/