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Peer-reviewed veterinary case report

Canine kobuvirus found in diarrheic dogs with parvovirus coinfection

By Miyabe, Flavia Megumi et al.·Published in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]·2019·Laboratory of Animal Virology, Brazil·View original on PubMed

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Original publication title: Detection of canine kobuvirus RNA in diarrheic fecal samples of dogs with parvoviruses.

Species:
dog

Plain-English summary

Three dogs with diarrhea were tested for canine kobuvirus (CaKV) in southern Brazil, and the virus was found in 5.7% of the samples. All dogs that tested positive for CaKV were also infected with canine parvovirus, which is known to cause severe gastrointestinal issues. This suggests that CaKV might be present in dogs with diarrhea, but it often occurs alongside other infections like parvovirus. The findings highlight the importance of testing for multiple viruses when dogs show signs of gastrointestinal distress.

People also search for: dog diarrhea causes · canine parvovirus treatment · what is canine kobuvirus · dog gastroenteritis symptoms

Abstract

Canine kobuvirus (CaKV) is a member of the Picornaviridae family and the Kobuvirus genus. CaKV was first described in fecal samples from diarrheic dogs in the USA in 2011, with subsequent reports in the UK, Italy, South Korea, China, Tanzania, and Japan. CaKV is frequently identified in feces of animals with or without clinical signs of gastroenteritis. The present study investigated the presence of CaKV in fecal samples from 53 diarrheic dogs from Londrina, southern Brazil. Using a RT-PCR assay, CaKV RNA was identified in three dogs, resulting in an overall occurrence rate of 5.7%. In addition, coinfection with canine parvovirus subtype 2b was detected in all CaKV-positive diarrheic fecal samples. Using a phylogenetic analysis based on the VP1 gene sequence, the Brazilian CaKV field strains were found to be very similar to a previously identified CaKV strain from Brazil that was found in the tissue of a puppy and were also found to be clustered with other CaKV strains detected worldwide and other kobuvirus strains identified in mouse, feline, and human hosts.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31140097/